About RevBio

For RevBio, the revolution started here, in Massachusetts.  It also started in nature with bio-inspiration from an amazing marine animal known as the Sandcastle Worm. Headquartered in Lowell, the company includes an extensive team of scientists, engineers, and clinicians who have reverse engineered a mineral-organic compound into a patented bioadhesive with an extensive platform of bone repair applications. A MassChallenge start-up accelerator alum, RevBio has won over 10 grants, received multiple patents, and is conducting its first-in-human clinical trial on its biomimetic bone adhesive.

Brian Hess, MBA
Chief Executive Officer, Founder

Brian founded RevBio in 2014 with the goal of commercializing Tetranite®, a regenerative bone adhesive with 6+ patents. The game changing biomaterial platform promises to transform bone repair across a body of human and animal indications. Brian previously co-invented this technology while at Stryker Corporation where he received the 2010 Innovator of the Year Award for this novel invention. During his tenure at Stryker, Brian also developed and launched HydroSet™, a commercially successful synthetic bone substitute, which is a key predicate to RevBio’s Tetranite technology. Prior to founding RevBio, Brian was the Chief Technology Officer at InVivo Therapeutics where he led the R&D organization which developed a class III biomaterial that gained FDA approval (to evaluate its use in clinical trials for treating patients with traumatic spinal cord injury). Brian is co-inventor and holder of over twelve patents. He received his BS in Mechanical Engineering from the UW-Madison and his MBA from the MIT Sloan School of Management.

D. Grayson Allen, MBA
Chief Operations Officer & CFO

Grayson has served as the Chief Financial Officer at AeroSat Corporation, North American Industries, and, most recently, has served as an interim CFO for multiple organizations as an Engagement Partner with Tatum, a management consulting firm. His past interim CFO engagements include working with several diagnostics, medical device, and healthcare companies. He has over sixteen years of experience in providing strategic financial leadership, creating and managing finance teams, implementing the infrastructure and processes necessary for rapid growth and expansion, and has raised over $120 million in cumulative investment capital during his career to date. Grayson also has previous venture capital experience and received his BA from Dartmouth College and his MBA from the MIT Sloan School of Management.

George Kay, DMD
Chief Scientific Officer

George has been a teaching clinical faculty member at Harvard School of Dental Medicine for over 30 years, currently teaching in the Advanced Graduate Prosthodontics and Periodontology programs. He has been involved in both clinical and basic science research in material science and dental implants and is an inventor with several patents to his credit. He is a Diplomate of the American Board of Implant Dentistry and has lectured extensively on bone grafting and implants in the USA and abroad. Dr. Kay holds a Sc.B. in Biochemistry from Brown University (1976), and D.M.D. (1980) and M.M.Sc. in Oral Biology (1984) from Harvard University.

Joseph P. Fiorellini, DMD, DMSc
Chairman, Dental Advisory Board

Dr. Fiorellini joined Penn Dental Medicine in 2005, serving as Chair of the Department and Director of the Postdoctoral Periodontics Program through June 2015. Prior to joining Penn Dental Medicine, Dr. Fiorellini was at Harvard School of Dental Medicine, where he served as Vice Chair and Associate Professor of the Department of Oral Medicine, Infection and Immunity; Head of the Division of Periodontology; and Program Director of Periodontology. His areas of research include the relationship of genetics and periodontal disease and studies related to periodontal regeneration and implantology. Dr. Fiorellini currently serves on the editorial boards of the Journal of Periodontology, the International Journal of Oral and Maxillofacial Implants and the International Journal of Periodontics and Restorative Dentistry. He has authored more than 50 manuscripts, reviews, and textbook chapters.

Michael R. Norton, BDS, FDS, RCS (Ed)

Dr. Michael Norton graduated from the University of Wales College of Medicine Dental School in Cardiff in 1988.  He received further training in Oral and Maxillofacial Surgery at St. Thomas Hospital London, and the Royal London Hospital and subsequently fulfilled the General Dental Council requirements to be certified as a specialist in Oral Surgery. Dr Norton’s practice has been a leading center for dental implants in the United Kingdom for over 25 years where he runs his private practice, Norton Implants is located on Harley Street, famed for being home to some of world’s most prestigious medical specialist practices. In 2007 Dr Norton was awarded the prestigious Fellowship of the Royal College of Surgeons, Edinburgh, where he served on the Specialist Advisory Board to help establish the Royal College Diploma in Implant Dentistry. He was the first ever non-American President of the US-based Academy of Osseointegration (AO) in 2017 and also President of the Association of Dental Implantology (UK) in 2000. Dr. Norton is currently Adjunct Clinical Professor in the Department of Periodontology at the University of Pennsylvania.

David L. Cochran, DDS, PhD, MMSci

Dr. Cochran currently serves as the chairman of the Department of Periodontics at The University of Texas Health Science Center San Antonio School of Dentistry. Prior to his appointment at San Antonio, Dr. Cochran was director of Postgraduate Periodontics at the Medical College of Virginia. Dr. Cochran is a member of many professional dental organizations and is a Diplomate of the American Board of Periodontology. He is a fellow of the American College of Dentistry and the International College of Dentistry. Dr. Cochran has published numerous scientific articles and abstracts on various periodontal, biochemistry, and implant topics. He has received awards for his research work at both the national and international levels. Dr. Cochran received his undergraduate degree from the University of Virginia and received his DDS, MS and PhD in Biochemistry from the Medical College of Virginia. He was trained in Periodontology at the Harvard School of Dental Medicine where he also obtained a second master’s degree. He recently received an Honorary Doctorate from the University of Bern in Switzerland.

Michael A. Pikos, DDS

Dr. Michael Pikos is founder and CEO of the Pikos Institute. Since 1990 he has been teaching advanced bone and soft tissue grafting courses with alumni that total more than 3,200 dentists from all 50 states and also from 43 different countries. Dr. Pikos maintains a private practice which is limited exclusively to implant surgery in Palm Harbor, Florida. He is a published author who has lectured extensively on dental implants in North and South America, Europe, Asia, and the Middle East. Dr. Pikos is also an active member and frequent lecturer for the American Association of Oral and Maxillofacial Surgeons, the American Academy of Periodontics, the Academy of Osseointegration, the American Academy of Implant Dentistry and the International Congress of Implantology. Dr. Pikos graduated from Ohio State University and also graduated with honors from The Ohio State University College of Dentistry.

Alan S. Pollack, DDS

Dr. Pollack has been a practicing periodontist in New York City for over  36 years. Dr. Pollack previously served as the President of the Academy of Osseointegration (AO) and has authored numerous articles in the field of implant dentistry. Besides his longstanding affiliation as a member and former Director of AO, he is also a member and Diplomate of the American Board of Periodontology. Dr. Pollack holds a BA from Queens College/CUNY and a DDS and a Certificate in Periodontics from Columbia University School of Dental Medicine. Dr. Pollack serves as the Chairman of the Company’s dental advisory board.

Paul A. Fugazzotto, DDS

Dr. Fugazzotto has authored and coauthored over 80 scientific articles, a monograph entitled “Guided Tissue Regeneration: Maximizing Clinical Results,” and three textbooks. He is currently a visiting lecturer at Tufts University, Harvard University, and The University of Ancona in Ancona, Italy. Dr. Fugazzotto lectures nationally and internationally on a multitude of topics and is Senior Editor of Implant Realities and serves as the US ITI Study Club Coordinator. He received his Doctorate of Dental Surgery from New York University, and his Certificate of Advanced Graduate Study from Boston University.

Alvaro Gracia, DMD

Dr. Alvaro Gracia has been practicing for over 22 years at his multi-specialty dental office, Advanced Dental Care of Norton in Norton, MA. He is a Fellow of the American Academy of Implant Dentistry, and a Diplomate of the American Board of Oral Implantology, where he also currently serves as a board examiner for the organization. He holds a DDS from Javeriana University in Colombia, a DMD from Boston University, and a CAGS in Prosthodontics from Boston University.

R. Bruce Donoff, DMD, MD

Dr. Bruce Donoff is the Dean of the Harvard School of Dental Medicine, a     post that he has held since 1991. In addition to these responsibilities, Dr. Donoff has made major contributions in research to the specialty of oral and maxillofacial surgery. Dr. Donoff served 12 years on the board of the Oral and Maxillofacial Surgery Foundation and is currently president of the Friends of the National Institute of Dental and Craniofacial Research. He is editor of the MGH Manual of Oral and Maxillofacial Surgery and a member of the editorial boards of the Journal of Oral and Maxillofacial Surgery and the Massachusetts Dental Society Journal. He attended Brooklyn College as an undergraduate, received his DMD from the Harvard School of Dental Medicine in 1967 and his MD from Harvard Medical School in 1973. Dr. Donoff has received numerous honors during his academic career, and has published more than 90 papers, authored textbooks, and lectured worldwide.

Michael J. Weaver, MD

Michael J. Weaver, MD, is the Chief of Orthopedic Trauma Surgery at Brigham and Women’s Hospital and is a clinical instructor of orthopedic surgery at Harvard Medical School. Dr. Weaver specializes in musculoskeletal trauma surgery. Dr. Weaver received his MD from UCLA School of Medicine and completed his Orthopedic Residency at the Harvard Combined Orthopedic Program. After residency, he completed an Orthopaedic Trauma Fellowship at the Massachusetts General Hospital.

Steven Z. Glickel, MD

Dr. Glickel is a prominent hand surgeon and former President of the American Society for Surgery of the Hand. He has been listed in the New York Magazine Best Doctors in New York every year since 1996, America’s Top Doctors yearly since 2001, Best Doctors in America since 2002 and Best Surgeons in America since 2005. He has contributed extensively to the literature in hand and orthopedic surgery and is a frequent lecturer and visiting professor at other Medical Centers. Dr. Glickel received his Doctor of Medicine degree from Harvard Medical School after which he completed a residency in Orthopedic Surgery at the Harvard Combined Orthopedic Program which included the MGH, Brigham and Women’s Hospital and Boston Children’s Hospital. Dr. Glickel provides user feedback on the design of the adhesive and delivery system for both open reduction internal fixation and closed percutaneous applications of the fracture fixation adhesive technology.

Jesse B. Jupiter, MD

Dr. Jupiter is the Hansjorg Wyss AO Professor of Orthopedic Surgery at Harvard Medical School and is an internationally known hand and upper limb specialist who practices at the Massachusetts General Hospital.  He is an honorary member of more than 20 international societies of either Hand Surgery or Orthopaedic Surgery and has been named to America’s Top Surgeons annually and Best of Boston since 2007.  Dr. Jupiter has given more than 1000 scientific presentations, published more than 220 original publications, 140 analytic reviews, 115 chapters in scientific texts and was co-author or co-editor of 10 major texts in upper limb and orthopaedic problems. He earned his BA from Brown University, his MD at Yale in 1972 and completed his surgical internship at the University of Pennsylvania Hospital in 1973.

Jonathan Dickens, MD

Jonathan (Jon) Dickens, MD is the Chief of the Orthopaedic Sports Medicine and Shoulder Service at Walter Reed National Military Medical Center (WRNMMC) in Bethesda, Maryland. He is Vice Chair of the Department of Surgery and Associate Professor of Surgery at the Uniformed Services University and is an Adjunct Faculty at the John A. Feagin Jr. Sports Medicine Fellowship at the United States Military Academy in West Point, New York.  He is also the Director of Orthopaedic Research at WRNMMC and Orthopaedic Consultant to the White House. He is Board Certified in Orthopaedic Surgery and is a Diplomat of the American Board of Orthopaedic Surgery. Dr. Dickens is a Lieutenant Colonel in the United States Army with experience and interests treating both combat-related orthopaedic injuries and sports injuries. Dr. Dickens provides formative user feedback on how TETRANITE can be applied to soft tissue applications for both the civilian and warfighter populations.

Art Coury, PhD

Dr. Coury holds a B.S. degree in chemistry from the University of Delaware (1962), a Ph.D. in organic chemistry (1965) and an M.B.A. (1980) from the University of Minnesota. His industrial career included positions as: Senior Research Chemist at General Mills, Inc. (1965-1976); Director, Polymer Technology and Research Fellow at Medtronic, Inc. (1976-1993); Vice President, Research and Chief Scientific Officer at Focal, Inc. (1993-2000); and Vice President, Biomaterials Research at Genzyme Corporation (2000- 2008).

Guiseppe Intini, DDS, PhD

Dr. Intini is an Associate Professor of Periodontics and Preventive Dentistry at the University of Pittsburgh, School of Dental Medicine. In addition, he is a visiting faculty at the Massachusetts General Hospital in Boston (MA), a part-time lecturer at the Harvard School of Dental Medicine in Boston (MA), and a Principal Faculty member of the Harvard Stem Cell Institute in Cambridge (MA).  Dr. Intini’s research interests include periodontal regeneration and bone augmentation procedures.  The basic science research in the INTINILAB focuses on skeletal stem cells and of bone cancer stem cells. Genetic strategies and in vivo imaging are utilized to describe the location and function of these cells and the molecular mechanisms that control their “stemness” in health and disease.  He is associate editor of the Journal of Translational Medicine and of Frontiers in Physiology.  Dr. Intini received his degree in dentistry from the University of L’Aquila (Italy), a MS in Oral Sciences from the University at Buffalo (NY), and a PhD in Oral Biology and a certificate in clinical Periodontology from the University at Buffalo (NY).  He is a Diplomate of the American Board of Periodontology.

Doug Van Citters, PhD

As  principal  investigator  of  the  Dartmouth Biomedical  Engineering  Center  for  Orthopaedics, Douglas  Van  Citters   oversees musculoskeletal, biomaterials, biomechanics, tribology, and device design research.  He is also responsible for curation and research activities related to Dartmouth’s arthroplasty retrieval collection.  His current research interests include polyethylene wear mechanisms at the micro- and nano- scales, fatigue properties of novel polyethylene formulations, wear and structure of alternative bearings for total hips, polymer structure, wearable technologies, and implantable technologies.  Professor Van Citters teaches Thayer School’s two graduate courses in biomaterials, as well as classical mechanics courses.  He has been an active collaborator and advisor in the biomaterials field for projects from the departments of orthopaedics, plastic surgery, pediatrics, radiology, physiology, and vascular surgery. Professor Van Citters received his BA from Dartmouth College and his BE, MA, and PhD from the Thayer School of Engineering at Dartmouth College.

Ken Gall, PhD

Professor Gall is currently the Chair of Mechanical Engineering and Materials Science at Duke University. His technical expertise is in the creation, modification, understanding, and commercialization of synthetic biomaterials. On the academic side, his materials publications have been cited approximately 16,000 times with an H-index of 69. On the commercial side, he has founded multiple medical device start-ups, including MedShape, Vertera, and Restor3d. MedShape is a fully functioning medical device company developing implants for foot and ankle reconstruction based on shape memory materials. MedShape’s sports medicine division was acquired by Conmed (NASDAQ:CNMD).  Vertera created the first spinal fusion implants based on porous polymer technologies and was acquired by Nuvasive (NASDAQ:NUVA). Restor3d is a new venture utilizing 3D printing of polymers and metals to create unique patient-specific implants on demand across multiple fields of medicine.  Professor Gall received his BS, MS, and PhD from the University of Illinois Champaign-Urbana in Mechanical Engineering.

Gino DeSimone

Gino DeSimone brings over 25 years of sales, marketing, and education experience in progressive leadership roles within the dental industry. Gino has successfully served as EVP of Professional Development for ClearChoice Dental Implant Centers, SVP Sales for RODO Medical, SVP Sales & Marketing Lending Club Patient Solutions, SVP Sales & Marketing Straumann North American, Sales Executive at Discus Dental and Global Product Management Leader at 3M Unitek (now 3M Oral Care).  Over the years, Gino has effectively worked with clinical researchers, thought leaders and KOLs alike helping deliver powerful corporate forum and clinical CE to the dental community. In addition to his advisory capacity with RevBio, Gino currently serves as Board Advisor for Supply Clinic, as a member of the Dean’s Advisory Board at A.T. Still University Arizona School of Dentistry & Oral Health and Director on the Board at Medical Mission of Mercy USA.

Frank Caine

Franklyn A. Caine is an independent consultant. His clients have included venture and start-up situations, private equity sponsors and small or mid-cap companies facing either extraordinary growth opportunities or restructuring challenges. His areas of emphasis are operations analysis, business planning financing strategy, working capital management and M&A advisory work. Earlier in his career, Frank was Senior Vice President and Chief Financial Officer of Raytheon Company, from early-1999 through early-2003. There, he focused on driving improvements in working capital efficiency and operating cash flow and, as a result, in Raytheon’s leverage and credit quality. Prior to joining Raytheon, Frank served as Executive Vice President and Chief Financial Officer of Wang for the four years following Wang’s bankruptcy and reorganization. Frank earned a bachelor’s degree in chemical engineering from Princeton University and an MBA in finance and international business from the University of Chicago.

Rick Gennett

Mr. Gennett served as the President of Synthes Trauma Inc. from 1995 to 2010, just prior to its sale to Johnson & Johnson for $20.2 billion. During his tenure as President, the Trauma Division grew from $185 million to $1.3 billion and reached the number one market share position based on new product development initiatives and innovative sales strategies. Rick also served as Vice President of Sales, National Sales Manager, and Regional Sales Manager during his first ten years at Synthes.  Prior to joining Synthes, Mr. Gennett worked at the Ethicon Division of Johnson & Johnson for ten years in various positions including Regional Sales Manager, Product Manager, Marketing Research Manager, and Sales Representative.  Mr. Gennett has served as a member of the Board of Directors at CD Diagnostics, HD Lifesciences, EWAVi, Tri-Medics, and Laschal Surgical Instruments. Mr. Gennett graduated with a BA in Psychology from Wilkes University.

Kevin Foley, MD
Chief Medical Officer

Dr. Foley is a professor in the Departments of Neurosurgery and Orthopaedic Surgery & Biomedical Engineering at the University of Tennessee Health Science Center in Memphis, Tennessee.  He is the chairman of Semmes-Murphey Clinic, director of the spine fellowship program for the University of Tennessee Department of Neurosurgery, and chairman of the board and medical director for the Medical Education & Research Institute.  Dr. Foley received his Doctor of Medicine degree from UCLA in 1979. He completed a neurosurgery residency at UCLA in 1985.  Following residency, Dr. Foley served in the United States Army Medical Corps as Assistant Chief of Neurosurgery at Brooke Army Medical Center, Chief of Neurosurgery at Tripler Army Medical Center, and Chief of Neurosurgery at Walter Reed Army Medical Center, where he was also the chairman of the neurosurgical residency training program.  In 1992, Dr. Foley left the military and joined Semmes-Murphey Clinic and the Department of Neurosurgery at UTHSC.  In addition to a full-time spine surgery practice, he is actively involved in research in minimally invasive spine surgery, image-guided spinal navigation, robotics, spinal biomechanics, clinical outcomes, and disc regeneration.  He has over 200 scientific publications to his credit, has lectured at more than 600 scientific meetings and educational workshops, and has been a visiting professor and invited lecturer at numerous universities in the US and abroad.  In addition, Dr. Foley has been issued 180 U.S. patents; his inventions include tubular retractors for minimally invasive spinal surgery, methods and devices for image-guided surgery, minimally invasive spinal fixation using screws with percutaneous extenders, and bullet-nosed interbody implants.  In recognition of his accomplishments, Dr. Foley was presented with the American Association of Neurological Surgeons Cushing Award for Technical Excellence and Innovation in Neurosurgery in 2019.

Eric Woodard, MD

Dr. Woodard is the Chief of Neurosurgery at The New England Baptist Hospital where he oversees the Neurosurgery department and the associated fellowship program. He is a member of numerous professional societies including the American Association of Neurological Surgeons, the Congress of Neurological Surgeons, and the Joint section of the AANS/CNS for Spine and Peripheral nerve. He has also served extensively over the last 18 years as faculty, Board member, foundation trustee, and Chairman of the board of AOSpine North America. Dr. Woodard has been a member of the editorial board for The Journal of Spinal Disorders & Techniques and Spine Universe and is a reviewer for The New England Journal of Medicine and Neurosurgery. Dr. Woodard earned his medical degree from Pennsylvania State University, and completed his neurological surgery residency at Emory University in Atlanta.

Tim Smith, MD, PhD, MPH

Dr. Timothy Smith is a neurosurgeon-scientist who seeks to understand, predict, and improve clinical outcomes for neurosurgical patients. Trained as an epidemiologist and statistician in addition to his neurosurgical residency, he focuses primarily on the utilization of data science to optimize neurosurgical patient care. Dr. Smith is a committee vice-chair for Medical-Legal Issues with the Council of State Neurosurgical Societies (CSNS) as well as the President of the Boston Society for Neurology, Neurosurgery, and Psychiatry, the oldest academic neuroscience society in the United States. He serves on numerous committees both in the US and worldwide which focus on the ethics of neurosurgery, oncology, skull base surgery, and neurologic outcomes assessment. Dr. Smith maintains active membership in both national and international neurosurgical societies and presents his research regularly at meetings around the world. Dr. Smith provides formative feedback during user handling trials for TETRANITE’s Cranial Flap Fixation indication.

John Lazor, MD

Dr. Lazor is a double board certified Otolaryngology-Head and Neck Surgeon and Facial Plastic and Reconstructive Surgeon who completed his residency and fellowship at Harvard Medical School, Mass Eye and Ear Infirmary/Mass General Hospital in 1996. He performs both cosmetic and reconstructive surgery at Mass Eye and Ear Infirmary where he has operated for 30 years. He also completed his MBA from Boston University in 2001.

Jonathan Slotkin, MD

Dr. Slotkin is a clinical neurosurgeon and research scientist who has expertise in complex and minimally invasive spinal surgery, spinal oncology surgery, and brain tumor surgery. Dr. Slotkin completed residency training in neurosurgery at Harvard Medical School, Brigham and Women’s Hospital (2006). He performed a fellowship in complex spinal surgery and is currently director of spinal surgery and research at Geisinger Health System. At RevBio, Dr. Slotkin heads the neurospinal and orthopedic advisory team.

Michael Brown, Director of Research & Development

Mike is a seasoned program leader who has launched three Class II/III medical devices at Johnson & Johnson and InVivo Therapeutics. He holds the PMP professional distinction, is Six Sigma Black Belt trained, and is co- inventor of three patents. Mike received his BS in Mechanical Engineering with a focus in Bioengineering and a General Management Diploma from the Rochester Institute of Technology and a Masters in Engineering Management from the MIT Sloan School of Management.

Gary Bunnewith, Director of Quality Control

Gary has a deep domain expertise in quality management in the medical device industry. He started his career at CR Bard where he served as a Quality Engineer. Gary spent over 10 years at Boston Scientific and subsequently held the role of Director of Quality and Regulatory for 15 year at TechDevice Corporation, a Boston Scientific spin out, and Vice President of Quality and Compliance. For the past three years he has served as Director of Quality for LaunchPad Medical. Gary received his MS in Quality Management from Anna Maria College.

David Koch, Advanced Manufacturing Manager

David possesses a deep background in the fabrication, testing, and documentation of medical devices. In his 20-plus years within the medical device industry he has helped launch several Class II/III products.